Figure 1

Comparison of changes in mean (± SEM) oedema volume (in ml) over 360 days between patients treated with Daflon (500 mg) + DEC (25 mg), and patients treated with DEC (25 mg), twice daily for 90 days. Day 0: pre-treatment Day 1 – day 90 period of treatment Day 91 – day 360 period of follow-up *P = < 0.05 vs. day 0 **P = < 0.005 vs. day 0 ***P = < 0.001 vs. day 0